With Tyrese Gibson & Mark Wahlberg / Four Brothers is a 2005 American action film directed by John Singleton. The film stars Mark Wahlberg, Tyrese Gibson, André Benjamin and Garrett Hedlund as four adopted brothers who set out to avenge the murder of their adoptive mother. The film was shot in Detroit, Michigan and the Greater Toronto Area. It has been described as blaxploitation-influenced. Released on August 12, 2005, the film received mixed reviews from critics and grossed $92 million worldwide.

An elderly woman, Evelyn Mercer, is murdered at a convenience store in Highland Park, Michigan when a robbery occurs that results in the death of the store clerk, and Evelyn was left as the one and only witness. The incident brings her four adoptive sons back home to Detroit, Michigan to find out what happened.

The oldest is a lifelong criminal, hot-tempered Bobby; the second oldest is family man and Union construction worker Jeremiah; the third oldest is an ex-hustler and former US Marine, Angel; and the youngest is aspiring rock musician Jack. Originally under the impression the crime was a simple robbery gone wrong, the brothers chase down and interrogate a false witness to the police, after which the brothers discover that the robbery was a cover for a hit put out on Evelyn.

The brothers track down the pair of hired guns who shot and killed Evelyn, and after refusing to give up any information, the two hitmen are executed by the enraged Bobby and Angel. The next day, Detroit Police Lieutenant Green and Detective Fowler confront the brothers about the murders. While the brothers deny involvement, Lieutenant Green warns them that their interference with Evelyn’s case is ill-advised and that it will put them in over their heads