Resident Evil: Apocalypse is a science fiction horror film directed by Alexander Witt. The story continues from the first film, focusing on Alice (Milla Jovovich) as she navigates the chaos unleashed by the T-virus in Raccoon City. After the outbreak, the city is overrun by zombies and other mutated creatures.

Alice teams up with a group of survivors, including a former police officer and a scientist, to escape the city and stop the Umbrella Corporation from further spreading the virus. As they battle hordes of undead and face off against the powerful mutant Nemesis, the film explores themes of survival and the fight against corporate evil in a world plunged into apocalyptic ruin.